2'-Fluoro-2-isopropylsulfanyl-5'-methoxy-biphenyl-4-carboxylic acid methyl ester → 2-[4-(Chloromethyl)-2-propan-2-ylsulfanylphenyl]-1-fluoro-4-methoxybenzene
Reaction equation
[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][c:7]([S:20][CH:21]([CH3:22])[CH3:23])[c:8](-[c:11]2[c:12]([F:19])[cH:13][cH:14][c:15]([O:17][CH3:18])[cH:16]2)[cH:9][cH:10]1.[Cl:24][CH2:25][c:26]1[cH:27][cH:28][c:29](-[c:30]2[cH:31][c:32]([O:33][CH3:34])[cH:35][cH:36][c:37]2[F:38])[c:39]([C:40]([CH3:41])([CH3:42])[CH3:43])[cH:44]1>>[CH2:3]([c:5]1[cH:6][c:7]([S:20][CH:21]([CH3:22])[CH3:23])[c:8](-[c:11]2[c:12]([F:19])[cH:13][cH:14][c:15]([O:17][CH3:18])[cH:16]2)[cH:9][cH:10]1)[Cl:24]Participants
3
Sources & evidence
- ORD record
- ord-a21c87aa40a548938ec94e2ecab3fe12
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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