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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 942974Generated: October 25, 2026

1,4-Dioxane → 2-(1-((2-(2-ethyl-2H-indazol-3-yl)-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-4-yl)propan-2-ol

https://huagongshe.com/reaction/942974

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DioxaneHCID 31275—
ReactantCopper(1+)HCID 104815—
ReactantThiophene-2-carboxylateHCID 5017639—
Reactant2-(1-((4-Morpholino-2-(tributylstannyl)pyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-4-yl)propan-2-olHCID 58404980—
ReactantHCID 67342953HCID 67342953—
ReactantHCID 178420554HCID 178420554—
Product2-(1-((2-(2-ethyl-2H-indazol-3-yl)-4-morpholinopyrido[3,2-d]pyrimidin-6-yl)methyl)piperidin-4-yl)propan-2-olHCID 53378676—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-37bc301b832e40328ff4198628a64d5f
Source noteValidation data from https://doi.org/10.1039/C8SC04228D