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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 943009Generated: October 27, 2026

1,3-Difluorobenzene → 1-(2-{4-[2-(3,5-Difluoro-phenyl)-6-methoxy-naphthalen-1-yloxy]-phenoxy}-ethyl)-piperidine

https://huagongshe.com/reaction/943009

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-DifluorobenzeneHCID 9741—
ReactantFluoride IonHCID 28179—
ReactantBoronic AcidHCID 61668—
ReactantTricyclohexylphosphineHCID 75806—
ReactantCesium cationHCID 104967—
Reactant6-Methoxy-1-(4-(2-(piperidin-1-yl)ethoxy)phenoxy)naphthalen-2-yl trifluoromethanesulfonateHCID 11613376—
Product1-(2-{4-[2-(3,5-Difluoro-phenyl)-6-methoxy-naphthalen-1-yloxy]-phenoxy}-ethyl)-piperidineHCID 57552561—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-63dfe341245b4165b55e78649e370f11
Source noteValidation data from https://doi.org/10.1039/C8SC04228D