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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 943017Generated: October 30, 2026

Methanol → [4-(2-Cyclopropyl-4,4-dimethyl 1,2,3,4-tetrahydro-isoquinoline-6-yl-ethynyl)-2-fluoro-phenyl]-acetic Acid

https://huagongshe.com/reaction/943017

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantHydroxideHCID 961—
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
Reactant[4-(2-Cyclopropyl-4,4-dimethyl-1,2,3,4-tetrahydro-isoquinolin-6-ylethynyl)-2-fluoro-phenyl]-acetic acid ethyl esterHCID 69548286—
Product[4-(2-Cyclopropyl-4,4-dimethyl 1,2,3,4-tetrahydro-isoquinoline-6-yl-ethynyl)-2-fluoro-phenyl]-acetic AcidHCID 10134200—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-7798116240314ad19287892f4ea95364
Source noteValidation data from https://doi.org/10.1039/C8SC04228D