Dichloromethane → N-({3'-[(4-Cyano-1-piperidinyl)methyl]-6-fluoro-3-biphenylyl}methyl)-N'-{[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}-1,3-benzenedicarboxamide
Reaction equation
[CH2:1]([CH3:2])[n:3]1[n:4][cH:5][c:6]2[c:7]1[n:8][c:9]([CH2:48][CH3:49])[c:10]([CH2:19][NH:20][C:21](=[O:22])[c:23]1[cH:24][c:25]([C:29](=[O:30])[NH:31][CH2:32][c:33]3[cH:34][c:35](-[c:40]4[cH:41][c:42]([CH:46]=[O:47])[cH:43][cH:44][cH:45]4)[c:36]([F:39])[cH:37][cH:38]3)[cH:26][cH:27][cH:28]1)[c:11]2[NH:12][CH:13]1[CH2:14][CH2:15][O:16][CH2:17][CH2:18]1.[Cl:58][CH2:59][Cl:60].[NH:50]1[CH2:51][CH2:52][CH:53]([C:56]#[N:57])[CH2:54][CH2:55]1>>[CH2:1]([CH3:2])[n:3]1[n:4][cH:5][c:6]2[c:7]1[n:8][c:9]([CH2:48][CH3:49])[c:10]([CH2:19][NH:20][C:21](=[O:22])[c:23]1[cH:24][c:25]([C:29](=[O:30])[NH:31][CH2:32][c:33]3[cH:34][c:35](-[c:40]4[cH:41][c:42]([CH2:46][N:50]5[CH2:51][CH2:52][CH:53]([C:56]#[N:57])[CH2:54][CH2:55]5)[cH:43][cH:44][cH:45]4)[c:36]([F:39])[cH:37][cH:38]3)[cH:26][cH:27][cH:28]1)[c:11]2[NH:12][CH:13]1[CH2:14][CH2:15][O:16][CH2:17][CH2:18]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-2bc9207fdf7b42cf8f0d1c08ea562cbb
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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