3-Bromo-5-chloropyridine → 2-tert-Butyl-6-(5-chloro-pyridin-3-ylethynyl)-pyrazolo[1,5-a]pyrimidine

HRID 943164Notes

Reaction equation

HRID 943164 reaction equation
[Br:16][c:17]1[cH:18][n:19][cH:20][c:21]([Cl:23])[cH:22]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][n:7]2[c:8]([n:9][cH:10][c:11]([C:13]#[CH:14])[cH:12]2)[cH:15]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[n:6][n:7]2[c:8]([n:9][cH:10][c:11]([C:13]#[C:14][c:17]3[cH:18][n:19][cH:20][c:21]([Cl:23])[cH:22]3)[cH:12]2)[cH:15]1

Participants

3

Reactant 2

HCID 6062563-Bromo-5-chloropyridineHCID 583167022-tert-Butyl-6-ethynyl-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 532473302-tert-Butyl-6-(5-chloro-pyridin-3-ylethynyl)-pyrazolo[1,5-a]pyrimidine

Sources & evidence

ORD record
ord-00f2b831a6bf4295a8dc56492aa30285
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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