Dichloromethane → {4-[(3-Methyl-pyridin-2-ylmethyl)-(1-pyrazin-2-yl-ethyl)-amino]-butyl}-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][CH2:10][CH2:11][NH:12][CH:13]([CH3:14])[c:15]1[n:16][cH:17][cH:18][n:19][cH:20]1)=[O:21].[CH3:22][c:23]1[c:24]([CH:29]=[O:30])[n:25][cH:26][cH:27][cH:28]1.[Cl:31][CH2:32][Cl:33]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][CH2:10][CH2:11][N:12]([CH:13]([CH3:14])[c:15]1[n:16][cH:17][cH:18][n:19][cH:20]1)[CH2:29][c:24]1[c:23]([CH3:22])[cH:28][cH:27][cH:26][n:25]1)=[O:21]Participants
4
Sources & evidence
- ORD record
- ord-547a6ca6035c4d03968540158c9663b9
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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