Dimethyl Sulfoxide → Ethyl 2-(cyclopropylamino)-3,6-difluoro-4-[3-[(2-methylpropan-2-yl)oxycarbonylamino]pyrrolidin-1-yl]benzoate
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[c:6]([F:26])[c:7]([F:25])[c:8]([N:12]2[CH2:13][CH:14]([NH:17][C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:15][CH2:16]2)[cH:9][c:10]1[F:11])=[O:27].[CH3:32][S:33](=[O:34])[CH3:35].[CH:28]1([NH2:31])[CH2:29][CH2:30]1>>[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[c:6]([NH:31][CH:28]2[CH2:29][CH2:30]2)[c:7]([F:25])[c:8]([N:12]2[CH2:13][CH:14]([NH:17][C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:15][CH2:16]2)[cH:9][c:10]1[F:11])=[O:27]Participants
4
Sources & evidence
- ORD record
- ord-4dd909e39108401ba8aef4452da894cd
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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