Methanol → 4-[2-fluoro-4-(3-hydroxypropyl)anilino]-N-(3-hydroxypropyl)-1-methyl-6-oxo-1,6-dihydro-3-pyridinecarboxamide
Reaction equation
[CH3:28][OH:29].[F:1][c:2]1[c:3]([NH:4][c:5]2[c:6]([C:13](=[O:14])[NH:15][CH2:16][CH2:17][CH2:18][OH:19])[cH:7][n:8]([CH3:12])[c:9](=[O:11])[cH:10]2)[cH:20][cH:21][c:22]([C:24]#[C:25][CH2:26][OH:27])[cH:23]1>>[F:1][c:2]1[c:3]([NH:4][c:5]2[c:6]([C:13](=[O:14])[NH:15][CH2:16][CH2:17][CH2:18][OH:19])[cH:7][n:8]([CH3:12])[c:9](=[O:11])[cH:10]2)[cH:20][cH:21][c:22]([CH2:24][CH2:25][CH2:26][OH:27])[cH:23]1Participants
3
Sources & evidence
- ORD record
- ord-e4ee67d1474d4d6e97f08b5d8aa42247
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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