7-Aminoquinoline → 6-(2,3-Difluorophenyl)-2-methyl-N-quinolin-7-yl-nicotinamide
Reaction equation
[F:12][c:13]1[c:14](-[c:20]2[n:21][c:22]([CH3:29])[c:23]([C:24](=[O:25])[OH:26])[cH:27][cH:28]2)[cH:15][cH:16][cH:17][c:18]1[F:19].[NH2:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][cH:7][cH:8][n:9][c:10]2[cH:11]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[cH:6][cH:7][cH:8][n:9][c:10]2[cH:11]1)[C:24]([c:23]1[c:22]([CH3:29])[n:21][c:20](-[c:14]2[c:13]([F:12])[c:18]([F:19])[cH:17][cH:16][cH:15]2)[cH:28][cH:27]1)=[O:25]Participants
3
Sources & evidence
- ORD record
- ord-746380ba19114c41816bb60e12b0d345
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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