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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 943283Generated: October 31, 2026

Methyl acetoacetate → Methyl 7-[3-(4-fluorophenyl)-2-bicyclo[3.2.1]oct-2-enyl]-5-hydroxy-3-oxohept-6-enoate

https://huagongshe.com/reaction/943283

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl acetoacetateHCID 7757—
ReactantTetrahydrofuranHCID 8028—
Reactant3-[3-(4-Fluorophenyl)bicyclo[3.2.1]oct-2-en-2-yl]-propenalHCID 53727548—
ReactantButyllithiumHCID 178418339—
ProductMethyl 7-[3-(4-fluorophenyl)-2-bicyclo[3.2.1]oct-2-enyl]-5-hydroxy-3-oxohept-6-enoateHCID 54493557—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-1c58961adf5940e1b7dab7d7d93e22a7
Source noteValidation data from https://doi.org/10.1039/C8SC04228D