Ammonium → 5-bromo-7-[2-(4-morpholinyl)ethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

HRID 943305Notes

Reaction equation

HRID 943305 reaction equation
[Br:1][c:2]1[cH:3][n:4]([CH2:12][CH2:13][N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[c:5]2[n:6][cH:7][n:8][c:9]([Cl:11])[c:10]12.[NH4+:20].[OH-:21]>>[Br:1][c:2]1[cH:3][n:4]([CH2:12][CH2:13][N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[c:5]2[n:6][cH:7][n:8][c:9]([NH2:20])[c:10]12

Participants

4

Reactant 3

HCID 223AmmoniumHCID 961HydroxideHCID 866636825-bromo-4-chloro-7-[2-(4-morpholinyl)ethyl]-7H-pyrrolo[2,3-d]pyrimidine

Product 1

HCID 668240265-bromo-7-[2-(4-morpholinyl)ethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-8ab18abc1e434f70b9e75583f2900694
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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