3-[(6,7-Dimethoxy-4-quinazolinyl)oxy]aniline → 1-(3-(6,7-Dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(2-fluoropropan-2-yl)isoxazol-3-yl)urea
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[cH:17][c:18]([NH2:19])[cH:20][cH:21][cH:22]3)[n:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14].[F:23][C:24]([CH3:25])([CH3:26])[c:27]1[cH:28][c:29]([NH:32][C:33]([O:34][c:36]2[cH:37][cH:38][c:39]([Cl:40])[cH:41][cH:42]2)=[O:35])[n:30][o:31]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:15][c:16]3[cH:17][c:18]([NH:19][C:33]([NH:32][c:29]4[cH:28][c:27]([C:24]([F:23])([CH3:25])[CH3:26])[o:31][n:30]4)=[O:34])[cH:20][cH:21][cH:22]3)[n:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14]Participants
3
Sources & evidence
- ORD record
- ord-ad4556ad03ab43f9aa5e805c08cc0b88
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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