Acetic Acid → 3-(5-acetylamino-4-chloro-2-fluorophenyl)-1-methyl-6-trifluoromethyl-2,4(1H,3H)-pyrimidinedione
Reaction equation
[CH3:23][C:24]([OH:25])=[O:26].[NH2:1][c:2]1[c:3]([Cl:22])[cH:4][c:5]([F:21])[c:6](-[n:8]2[c:9](=[O:20])[n:10]([CH3:19])[c:11]([C:15]([F:16])([F:17])[F:18])[cH:12][c:13]2=[O:14])[cH:7]1.[cH:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[NH:1]([c:2]1[c:3]([Cl:22])[cH:4][c:5]([F:21])[c:6](-[n:8]2[c:9](=[O:20])[n:10]([CH3:19])[c:11]([C:15]([F:16])([F:17])[F:18])[cH:12][c:13]2=[O:14])[cH:7]1)[C:24]([CH3:23])=[O:25]Participants
4
Sources & evidence
- ORD record
- ord-a4330521957e4a1c8b0daac674ce3484
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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