Dichloromethane → N-[(1-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl]-N-{[3-(4-methylpiperazin-1-yl)-2,3,4,5-tetrahydrooxepin-3-yl]methyl}cyclohexanecarboxamide
Reaction equation
[CH3:1][n:2]1[c:3](=[O:29])[c:4]([CH2:12][NH:13][CH2:14][C:15]2([N:22]3[CH2:23][CH2:24][N:25]([CH3:28])[CH2:26][CH2:27]3)[CH2:16][O:17][CH:18]=[CH:19][CH2:20][CH2:21]2)[cH:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12.[CH:30]1([C:36](=[O:37])[Cl:38])[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35]1.[Cl:39][CH2:40][Cl:41]>>[CH3:1][n:2]1[c:3](=[O:29])[c:4]([CH2:12][N:13]([CH2:14][C:15]2([N:22]3[CH2:23][CH2:24][N:25]([CH3:28])[CH2:26][CH2:27]3)[CH2:16][O:17][CH:18]=[CH:19][CH2:20][CH2:21]2)[C:36]([CH:30]2[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35]2)=[O:37])[cH:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-3f8d2c4d13d240c6915277efa9a1d25b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…