Acetic Acid → 2-(2-Iodo-4-methoxyphenyl)-6-methoxy-1,2,3,4-tetrahydronaphthalene

HRID 943936Notes

Reaction equation

HRID 943936 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH:10]2[CH2:11][c:12]3[cH:13][cH:14][c:15]([O:20][CH3:21])[cH:16][c:17]3[CH2:18][CH2:19]2)[c:7]([NH2:9])[cH:8]1.[CH3:36][C:37](=[O:38])[OH:39].[I-:32].[I-:33].[K+:31].[N:27]([O-:28])=[O:29].[NH3:34].[Na+:30].[OH2:35].[S:22](=[O:23])(=[O:24])([OH:25])[OH:26]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH:10]2[CH2:11][c:12]3[cH:13][cH:14][c:15]([O:20][CH3:21])[cH:16][c:17]3[CH2:18][CH2:19]2)[c:7]([I:32])[cH:8]1

Participants

10

Reactant 9

HCID 176Acetic AcidHCID 222AmmoniaHCID 813Potassium CationHCID 923Sodium ionHCID 946NitriteHCID 962WaterHCID 1118Sulfuric AcidHCID 30165Iodide Ion2×HCID 230872055-Methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenylamine

Product 1

HCID 230875592-(2-Iodo-4-methoxyphenyl)-6-methoxy-1,2,3,4-tetrahydronaphthalene

Sources & evidence

ORD record
ord-cd3a45c380034f72956a2503cfb17b21
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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