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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 943961Generated: November 2, 2026

Sodium ion → 4-(4-Chloro-phenyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/943961

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantTolueneHCID 1140—
Reactantp-BromochlorobenzeneHCID 7806—
ReactantPalladiumHCID 23938—
ReactantDibenzylidene acetoneHCID 95417—
ReactantBinap, (A+-)-HCID 634876—
Reactanttert-Butyl 3-methylpiperazine-1-carboxylateHCID 2756810—
Reactant2-Methylpropan-2-olateHCID 4574913—
Product4-(4-Chloro-phenyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl esterHCID 66757957—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-cf5723489fca4f36ab2adcbeed8e4fc8
Source noteValidation data from https://doi.org/10.1039/C8SC04228D