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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 944133Generated: October 30, 2026

Hydrochloric Acid → 4'-chloro-6',7'-dihydro-5'H-spiro[cyclopentane-1,8'-quinazolin]-2'-amine

https://huagongshe.com/reaction/944133

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
Reactant1,4-DioxaneHCID 31275—
Reactant2'-amino-6',7'-dihydro-5'H-spiro[cyclopentane-1,8'-quinazolin]-4'-yl 4-methylbenzenesulfonateHCID 86634333—
Product4'-chloro-6',7'-dihydro-5'H-spiro[cyclopentane-1,8'-quinazolin]-2'-amineHCID 86634334—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-3eba1a03c2d344d2a7e458c0405e859e
Source noteValidation data from https://doi.org/10.1039/C8SC04228D