Formic Acid → 2-Amino-4-chloro-5-formyl-3-thiophenecarbonitrile

HRID 944211Notes

Reaction equation

HRID 944211 reaction equation
[CH3:1][N:2]([CH3:3])[CH:15]=[N:4][c:5]1[s:6][c:7]([CH:13]=[O:14])[c:8]([Cl:12])[c:9]1[C:10]#[N:11].[CH:16]([OH:17])=[O:18].[OH2:19]>>[NH2:4][c:5]1[s:6][c:7]([CH:13]=[O:14])[c:8]([Cl:12])[c:9]1[C:10]#[N:11]

Participants

4

Reactant 3

HCID 284Formic AcidHCID 962WaterHCID 54382946N'-(4-chloro-3-cyano-5-formyl-2-thienyl)-N,N-dimethylformamidine

Product 1

HCID 27376122-Amino-4-chloro-5-formyl-3-thiophenecarbonitrile

Sources & evidence

ORD record
ord-0819815fb4db49c5ac10c82fe794f3f8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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