(3-Amino-4-methylphenyl)boronic acid → 5-[2-(1-Azabicyclo[2.2.2]oct-3-yloxy)pyrimidin-5-yl]-2-methylaniline
Reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]([O:8][CH:9]2[CH2:10][N:11]3[CH2:12][CH2:13][CH:14]2[CH2:15][CH2:16]3)[n:6][cH:7]1.[NH2:17][c:18]1[cH:19][c:20]([B:25]([OH:26])[OH:27])[cH:21][cH:22][c:23]1[CH3:24]>>[c:2]1(-[c:20]2[cH:19][c:18]([NH2:17])[c:23]([CH3:24])[cH:22][cH:21]2)[cH:3][n:4][c:5]([O:8][CH:9]2[CH2:10][N:11]3[CH2:12][CH2:13][CH:14]2[CH2:15][CH2:16]3)[n:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-5e4d31da42134ce29476718f838ff9e2
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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