Dichloromethane → 3-(4-(2,4-difluorobenzyloxy)-3-bromo-6-methyl-2-oxopyridin-1(2H)-yl)-4-methylbenzoic acid
Reaction equation
[Br:29][N:30]1[C:31](=[O:32])[CH2:33][CH2:34][C:35]1=[O:36].[Cl:37][CH2:38][Cl:39].[F:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[cH:7][c:8](=[O:23])[n:9](-[c:13]3[cH:14][c:15]([C:16](=[O:17])[OH:18])[cH:19][cH:20][c:21]3[CH3:22])[c:10]([CH3:12])[cH:11]2)[cH:24][cH:25][c:26]([F:28])[cH:27]1>>[F:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[c:7]([Br:29])[c:8](=[O:23])[n:9](-[c:13]3[cH:14][c:15]([C:16](=[O:17])[OH:18])[cH:19][cH:20][c:21]3[CH3:22])[c:10]([CH3:12])[cH:11]2)[cH:24][cH:25][c:26]([F:28])[cH:27]1Participants
4
Sources & evidence
- ORD record
- ord-eef57460f738484187ad90ad3922f55d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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