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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 944437Generated: October 26, 2026

Sodium ion → 9-(2-Fluoro-4-methylphenyl)-2-(4-hydroxycyclohexyl)-2,9-diazaspiro[4.5]decan-1-one

https://huagongshe.com/reaction/944437

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
Reactanttert-ButanolHCID 6386—
ReactantPalladiumHCID 23938—
Reactant18-Crown-6HCID 28557—
ReactantDibenzylidene acetoneHCID 95417—
Reactant2-(Di-tert-butylphosphino)biphenylHCID 2734215—
ReactantBenzene, 2-fluoro-1-iodo-4-methyl-HCID 2774524—
Reactant2-Methylpropan-2-olateHCID 4574913—
Reactant2-(4-Hydroxycyclohexyl)-2,9-diazaspiro[4.5]decan-1-oneHCID 57970939—
Product9-(2-Fluoro-4-methylphenyl)-2-(4-hydroxycyclohexyl)-2,9-diazaspiro[4.5]decan-1-oneHCID 66722366—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-f0d560bced574335b0ed1b0518bbb485
Source noteValidation data from https://doi.org/10.1039/C8SC04228D