Dichloromethane → 5-Benzylamino-2-(4-trifluoromethoxy-phenyl)-hexahydro-cyclopenta[c]pyrrol-1-one
Reaction equation
[Cl:30][CH2:31][Cl:32].[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([N:10]2[C:11](=[O:19])[CH:12]3[CH:13]([CH2:14]2)[CH2:15][C:16](=[O:18])[CH2:17]3)[cH:8][cH:9]1)([F:20])[F:21].[NH2:22][CH2:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1>>[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([N:10]2[C:11](=[O:19])[CH:12]3[CH:13]([CH2:14]2)[CH2:15][CH:16]([NH:22][CH2:23][c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[CH2:17]3)[cH:8][cH:9]1)([F:20])[F:21]Participants
4
Sources & evidence
- ORD record
- ord-9a326c4fe4da4363b636bdf1495016e8
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…