3-(2-Morpholin-4-ylethoxy)aniline → 2,6-Difluoro-N-[3-(3-{2-[(3-{[2-(4-morpholinyl)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}pyrazolo[1,5-a]pyridin-2-yl)phenyl]benzamide
Reaction equation
[Cl:17][c:18]1[n:19][cH:20][cH:21][c:22](-[c:24]2[c:25](-[c:33]3[cH:34][c:35]([NH:39][C:40]([c:41]4[c:42]([F:48])[cH:43][cH:44][cH:45][c:46]4[F:47])=[O:49])[cH:36][cH:37][cH:38]3)[n:26][n:27]3[c:28]2[cH:29][cH:30][cH:31][cH:32]3)[n:23]1.[O:1]1[CH2:2][CH2:3][N:4]([CH2:7][CH2:8][O:9][c:10]2[cH:11][c:12]([NH2:16])[cH:13][cH:14][cH:15]2)[CH2:5][CH2:6]1>>[O:1]1[CH2:2][CH2:3][N:4]([CH2:7][CH2:8][O:9][c:10]2[cH:11][c:12]([NH:16][c:18]3[n:19][cH:20][cH:21][c:22](-[c:24]4[c:25](-[c:33]5[cH:34][c:35]([NH:39][C:40]([c:41]6[c:42]([F:48])[cH:43][cH:44][cH:45][c:46]6[F:47])=[O:49])[cH:36][cH:37][cH:38]5)[n:26][n:27]5[c:28]4[cH:29][cH:30][cH:31][cH:32]5)[n:23]3)[cH:13][cH:14][cH:15]2)[CH2:5][CH2:6]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-983dede199494dd2943f02b6210ff328
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…