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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 944773Generated: October 25, 2026

Methane → {4-Bromo-3-[2-(1-methyl-pyrrolidine-2-yl)-ethoxy]-phenyl}-acetonitrile

https://huagongshe.com/reaction/944773

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethaneHCID 297—
ReactantDimethyl SulfoxideHCID 679—
ReactantPotassium CationHCID 813—
ReactantMethanolHCID 887—
ReactantHydroxideHCID 961—
ReactantDichloromethaneHCID 6344—
ReactantTriethylamineHCID 8471—
ReactantSulfuryl chlorideHCID 24648—
Reactant1-Methyl-2-pyrrolidineethanolHCID 93363—
Reactant4-Bromo-3-hydroxyphenylacetonitrileHCID 18446568—
ReactantMethanesulfonic acid 2-(1-methyl-pyrrolidin-2-yl)-ethyl esterHCID 44627019—
Product{4-Bromo-3-[2-(1-methyl-pyrrolidine-2-yl)-ethoxy]-phenyl}-acetonitrileHCID 18446567—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-4d4cb4e630ec4b6793b2276f929f0581
Source noteValidation data from https://doi.org/10.1039/C8SC04228D