5-[3,5-Bis(trifluoromethyl)phenyl]-3-(chloromethyl)-1,2,4-oxadiazole → 1-({5-[3,5-Bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile

HRID 944776Notes

Reaction equation

HRID 944776 reaction equation
[F:16][C:17]([c:18]1[cH:19][c:20](-[c:28]2[n:29][c:30]([CH2:33][Cl:34])[n:31][o:32]2)[cH:21][c:22]([C:24]([F:25])([F:26])[F:27])[cH:23]1)([F:35])[F:36].[F:1][C:2]([c:3]1[c:4]2[cH:5][cH:6][nH:7][c:8]2[cH:9][cH:10][c:11]1[C:12]#[N:13])([F:14])[F:15]>>[F:1][C:2]([c:3]1[c:4]2[cH:5][cH:6][n:7]([CH2:33][c:30]3[n:29][c:28](-[c:20]4[cH:19][c:18]([C:17]([F:16])([F:35])[F:36])[cH:23][c:22]([C:24]([F:25])([F:26])[F:27])[cH:21]4)[o:32][n:31]3)[c:8]2[cH:9][cH:10][c:11]1[C:12]#[N:13])([F:14])[F:15]

Participants

3

Reactant 2

HCID 27809575-[3,5-Bis(trifluoromethyl)phenyl]-3-(chloromethyl)-1,2,4-oxadiazoleHCID 674054494-(trifluoromethyl)-1H-indole-5-carbonitrile

Product 1

HCID 249838351-({5-[3,5-Bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Sources & evidence

ORD record
ord-dfae862917164cc0891b596ef7318962
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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