Toluene → 6-Fluoro-1-(piperidin-4-yl)indoline
Reaction equation
[CH2:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[N:15]1[CH2:16][CH2:17][CH:18]([N:21]2[CH2:22][CH2:23][c:24]3[cH:25][cH:26][c:27]([F:30])[cH:28][c:29]32)[CH2:19][CH2:20]1.[CH3:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[Cl:1][C:2]([O:3][CH:4]([Cl:5])[CH3:6])=[O:7]>>[NH:15]1[CH2:16][CH2:17][CH:18]([N:21]2[CH2:22][CH2:23][c:24]3[cH:25][cH:26][c:27]([F:30])[cH:28][c:29]32)[CH2:19][CH2:20]1Participants
4
Sources & evidence
- ORD record
- ord-1e75ae6b21a74335910e060e59da63f5
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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