Quipazine → 9-[4-(4-Quinolin-2-yl-piperazin-1-yl)-butyl]-9h-fluorene-9-carboxylic acid-3.4-difluoro-benzylamide
Reaction equation
[F:1][c:2]1[cH:3][c:4]([CH2:5][NH:6][C:7](=[O:8])[C:9]2([CH2:22][CH2:23][CH2:24][CH2:25][Br:26])[c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]3-[c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]32)[cH:27][cH:28][c:29]1[F:30].[N:31]1([c:37]2[n:38][c:39]3[cH:40][cH:41][cH:42][cH:43][c:44]3[cH:45][cH:46]2)[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]1>>[F:1][c:2]1[cH:3][c:4]([CH2:5][NH:6][C:7](=[O:8])[C:9]2([CH2:22][CH2:23][CH2:24][CH2:25][N:34]3[CH2:33][CH2:32][N:31]([c:37]4[n:38][c:39]5[cH:40][cH:41][cH:42][cH:43][c:44]5[cH:45][cH:46]4)[CH2:36][CH2:35]3)[c:10]3[cH:11][cH:12][cH:13][cH:14][c:15]3-[c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]32)[cH:27][cH:28][c:29]1[F:30]Participants
3
Sources & evidence
- ORD record
- ord-3f00aba820954f1091c975dd083e89c0
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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