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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 944896Generated: October 27, 2026

Water → 5-(4-Fluorophenyl)-6-{fluoro[4-(trifluoromethyl)phenyl]methyl}-7-isopropylspiro[chromen-2,1'-cyclobutan]-4(3H)-one

https://huagongshe.com/reaction/944896

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTolueneHCID 1140—
Reactant(Diethylamino)sulfur trifluorideHCID 123472—
Reactant5-(4-Fluorophenyl)-6-{hydroxy[4-(trifluoromethyl)phenyl]methyl}-7-isopropylspiro[chromen-2,1'-cyclobutan]-4(3H)-oneHCID 58003030—
Product5-(4-Fluorophenyl)-6-{fluoro[4-(trifluoromethyl)phenyl]methyl}-7-isopropylspiro[chromen-2,1'-cyclobutan]-4(3H)-oneHCID 58003046—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-4647c663db37431ead91b3547fdfc766
Source noteValidation data from https://doi.org/10.1039/C8SC04228D