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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 944906Generated: October 26, 2026

Potassium Cation → N-cyclopropyl-3-(8-(2,6-difluorophenyl)-2-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino}-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-4-yl)-5-fluoro-4-methylbenzamide

https://huagongshe.com/reaction/944906

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CationHCID 813—
ReactantWaterHCID 962—
ReactantCarbonate IonHCID 19660—
Reactant1,4-DioxaneHCID 31275—
Reactant4-Chloro-2-(2-hydroxy-1-hydroxymethyl-ethylamino)-8-(2,6-difluoro-phenyl)-8H-pyrido[2,3-d]pyrimidin-7-oneHCID 11951517—
ReactantN-cyclopropyl-3-fluoro-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamideHCID 21914563—
ProductN-cyclopropyl-3-(8-(2,6-difluorophenyl)-2-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino}-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-4-yl)-5-fluoro-4-methylbenzamideHCID 11947855—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-e28c2e1263a24d6b9ef556d7d29e959a
Source noteValidation data from https://doi.org/10.1039/C8SC04228D