HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 945002Generated: October 26, 2026
Water → 3-[5-bromo-4-[(2,4-difluorophenyl)methoxy]-6-oxopyrimidin-1-yl]-N-(1-hydroxypropan-2-yl)-4-methylbenzamide
https://huagongshe.com/reaction/945002
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 2-Aminopropanol | HCID 5126 | — |
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Reactant | Isobutyl chloroformate | HCID 62365 | — |
| Reactant | 3-[5-bromo-4-[(2,4-difluorobenzyl)oxy]-6-oxopyrimidin-1(6H)-yl]-4-methylbenzoic acid | HCID 21089275 | — |
| Product | 3-[5-bromo-4-[(2,4-difluorophenyl)methoxy]-6-oxopyrimidin-1-yl]-N-(1-hydroxypropan-2-yl)-4-methylbenzamide | HCID 21088998 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Validation data from https://doi.org/10.1039/C8SC04228D |
|---|
| ORD ID | ord-317debf5a41a40689862535d19beb8bc |
|---|
| Source note | Validation data from https://doi.org/10.1039/C8SC04228D |
|---|
