1-{2-[Methyl(6-oxohexanoyl)amino]ethyl}piperidin-4-yl biphenyl-2-ylcarbamate → 1-{2-[{6-[({5-[{3-[(tert-Butoxycarbonyl)(methyl)amino]propyl}(methyl)carbamoyl]-2-thienyl}methyl)(2,2-dimethylpropyl)amino]hexanoyl}(methyl)amino]ethyl}piperidin-4-yl biphenyl-2-ylcarbamate
Reaction equation
[CH3:1][C:2]([CH2:3][NH:4][CH2:5][c:6]1[cH:7][cH:8][c:9]([C:11](=[O:12])[N:13]([CH2:14][CH2:15][CH2:16][N:17]([C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH3:25])[CH3:26])[s:10]1)([CH3:27])[CH3:28].[c:29]1(-[c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[c:30]([NH:35][C:36]([O:37][CH:38]2[CH2:39][CH2:40][N:41]([CH2:44][CH2:45][N:46]([C:47]([CH2:48][CH2:49][CH2:50][CH2:51][CH:52]=[O:53])=[O:54])[CH3:55])[CH2:42][CH2:43]2)=[O:56])[cH:31][cH:32][cH:33][cH:34]1>>[CH3:1][C:2]([CH2:3][N:4]([CH2:5][c:6]1[cH:7][cH:8][c:9]([C:11](=[O:12])[N:13]([CH2:14][CH2:15][CH2:16][N:17]([C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH3:25])[CH3:26])[s:10]1)[CH2:52][CH2:51][CH2:50][CH2:49][CH2:48][C:47]([N:46]([CH2:45][CH2:44][N:41]1[CH2:40][CH2:39][CH:38]([O:37][C:36]([NH:35][c:30]2[c:29](-[c:57]3[cH:58][cH:59][cH:60][cH:61][cH:62]3)[cH:34][cH:33][cH:32][cH:31]2)=[O:56])[CH2:43][CH2:42]1)[CH3:55])=[O:54])([CH3:27])[CH3:28]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-82c0a2aed3fb4c4289920df9f1aed494
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…