2-(Chloromethyl)-5-cyclopropyl-1,3,4-thiadiazole → 5-Chloro-thiophene-2-carboxylic acid {2-[(5-cyclopropyl-[1,3,4]thiadiazol-2-ylmethyl)-(1-isopropyl-piperidin-4-yl)-sulfamoyl]-ethyl}-amide

HRID 945026Notes

Reaction equation

HRID 945026 reaction equation
[CH:11]([CH3:12])([CH3:13])[N:14]1[CH2:15][CH2:16][CH:17]([NH:20][S:21](=[O:22])(=[O:23])[CH2:24][CH2:25][NH:26][C:27](=[O:28])[c:29]2[s:30][c:31]([Cl:34])[cH:32][cH:33]2)[CH2:18][CH2:19]1.[Cl:1][CH2:2][c:3]1[s:4][c:5]([CH:8]2[CH2:9][CH2:10]2)[n:6][n:7]1>>[CH2:2]([c:3]1[s:4][c:5]([CH:8]2[CH2:9][CH2:10]2)[n:6][n:7]1)[N:20]([CH:17]1[CH2:16][CH2:15][N:14]([CH:11]([CH3:12])[CH3:13])[CH2:19][CH2:18]1)[S:21](=[O:22])(=[O:23])[CH2:24][CH2:25][NH:26][C:27](=[O:28])[c:29]1[s:30][c:31]([Cl:34])[cH:32][cH:33]1

Participants

3

Reactant 2

HCID 27576792-(Chloromethyl)-5-cyclopropyl-1,3,4-thiadiazoleHCID 119904785-Chloro-Thiophene-2-Carboxylic Acid [2-(1--Isopropyl-Piperidin-4-Ylsulfamoyl)-Ethyl]-Amide

Product 1

HCID 666248035-Chloro-thiophene-2-carboxylic acid {2-[(5-cyclopropyl-[1,3,4]thiadiazol-2-ylmethyl)-(1-isopropyl-piperidin-4-yl)-sulfamoyl]-ethyl}-amide

Sources & evidence

ORD record
ord-d6189012412b4f668d87f4a9033c1d66
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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