Methanol → N-[1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-1-ethylpyrazol-5-yl)thiophene-2-carboxamide
Reaction equation
[CH3:39][OH:40].[Cl:1][c:2]1[c:3](-[c:31]2[c:32]([Cl:38])[cH:33][n:34][n:35]2[CH2:36][CH3:37])[cH:4][c:5]([C:7](=[O:8])[NH:9][CH:10]([CH2:11][N:12]2[C:13](=[O:14])[c:15]3[c:16]([cH:17][cH:18][cH:19][cH:20]3)[C:21]2=[O:22])[CH2:23][c:24]2[cH:25][c:26]([F:30])[cH:27][cH:28][cH:29]2)[s:6]1>>[Cl:1][c:2]1[c:3](-[c:31]2[c:32]([Cl:38])[cH:33][n:34][n:35]2[CH2:36][CH3:37])[cH:4][c:5]([C:7](=[O:8])[NH:9][CH:10]([CH2:11][NH2:12])[CH2:23][c:24]2[cH:25][c:26]([F:30])[cH:27][cH:28][cH:29]2)[s:6]1Participants
3
Sources & evidence
- ORD record
- ord-696362980326421597949711b989bc15
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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