Dichloromethane → 4-bromo-5-(2,6-difluoro-3-nitrophenyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole
Reaction equation
[Br:23][N:24]1[C:25](=[O:26])[CH2:27][CH2:28][C:29]1=[O:30].[Cl:31][CH2:32][Cl:33].[F:1][c:2]1[c:3](-[c:12]2[cH:13][cH:14][n:15][n:16]2[CH:17]2[O:18][CH2:19][CH2:20][CH2:21][CH2:22]2)[c:4]([F:11])[cH:5][cH:6][c:7]1[N+:8](=[O:9])[O-:10]>>[F:1][c:2]1[c:3](-[c:12]2[c:13]([Br:23])[cH:14][n:15][n:16]2[CH:17]2[O:18][CH2:19][CH2:20][CH2:21][CH2:22]2)[c:4]([F:11])[cH:5][cH:6][c:7]1[N+:8](=[O:9])[O-:10]Participants
4
Sources & evidence
- ORD record
- ord-c11eaba12d934891ac1c2e5846d50e8a
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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