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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 945185Generated: October 27, 2026

Hydrogen Bromide → 1-[[[4-[2-(4-Methyl-1-piperazinyl)-4-thiazolyl]phenyl]carbonyl]amino]cyclohexanecarboxylic acid phenylmethyl ester

https://huagongshe.com/reaction/945185

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen BromideHCID 260—
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
Reactant4-[2-(4-Methyl-piperazin-1-yl)-thiazol-4-yl]-benzoic acidHCID 11652405—
ReactantBenzyl 1-aminocyclohexanecarboxylateHCID 15176238—
Product1-[[[4-[2-(4-Methyl-1-piperazinyl)-4-thiazolyl]phenyl]carbonyl]amino]cyclohexanecarboxylic acid phenylmethyl esterHCID 57672820—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-13b63514613d4cb8abc2fe94f564c3de
Source noteValidation data from https://doi.org/10.1039/C8SC04228D