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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 945230Generated: October 26, 2026

Dichloromethane → 7-Methyl-4-[3-(6-methyl-pyrazin-2-yl)-phenyl]-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-one

https://huagongshe.com/reaction/945230

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
Reactant(5-Methyl-2-{3-[3-(6-methyl-pyrazin-2-yl)-phenyl]-3-oxo-propionylamino}-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 86589310—
Product7-Methyl-4-[3-(6-methyl-pyrazin-2-yl)-phenyl]-8-trifluoromethyl-1,3-dihydro-benzo[b][1,4]diazepin-2-oneHCID 22317843—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-a3b65f47a84c41e3b3981ea7e00f4a2c
Source noteValidation data from https://doi.org/10.1039/C8SC04228D