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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 945479Generated: October 30, 2026

Acetic Acid → Methyl 4-bromo-5-[3-(cyclohexylamino)phenyl]-3-(2-ethoxy-2-oxoethoxy)thiophene-2-carboxylate

https://huagongshe.com/reaction/945479

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
ReactantCyclohexanoneHCID 7967—
ReactantTriacetoxyborohydrideHCID 2724942—
ReactantMethyl 5-(3-aminophenyl)-4-bromo-3-(2-ethoxy-2-oxoethoxy)thiophene-2-carboxylateHCID 68836370—
ProductMethyl 4-bromo-5-[3-(cyclohexylamino)phenyl]-3-(2-ethoxy-2-oxoethoxy)thiophene-2-carboxylateHCID 17759435—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-2dd3a46f7401435daa909135357edc18
Source noteValidation data from https://doi.org/10.1039/C8SC04228D