4-((3-Methoxyphenyl)amino)-8-methyl-6-((3-(4-(3-(2-oxopropyl)benzoyl)piperazine-1-carbonyl)phenyl)sulfonyl)quinoline-3-carboxamide → 6-[3-[4-[3-[2-[[2-[tert-butyl(dimethyl)silyl]oxy-2-(2-oxo-8-phenylmethoxy-1H-quinolin-5-yl)ethyl]amino]-2-methylpropyl]benzoyl]piperazine-1-carbonyl]phenyl]sulfonyl-4-(3-methoxyanilino)-8-methylquinoline-3-carboxamide
Reaction equation
[CH2:53]([c:54]1[cH:55][cH:56][cH:57][cH:58][cH:59]1)[O:60][c:61]1[cH:62][cH:63][c:64]([CH:72]([CH2:73][NH:74][C:75]([CH2:76][c:77]2[cH:78][c:79]([C:83]([OH:84])=[O:85])[cH:80][cH:81][cH:82]2)([CH3:86])[CH3:87])[O:88][Si:89]([CH3:90])([CH3:91])[C:92]([CH3:93])([CH3:94])[CH3:95])[c:65]2[cH:66][cH:67][c:68](=[O:71])[nH:69][c:70]12.[CH3:1][O:2][c:3]1[cH:4][c:5]([NH:9][c:10]2[c:11]([C:50](=[O:51])[NH2:52])[cH:12][n:13][c:14]3[c:15]([CH3:49])[cH:16][c:17]([S:20](=[O:21])(=[O:22])[c:23]4[cH:24][c:25]([C:29](=[O:30])[N:31]5[CH2:32][CH2:33][N:34]([C:37]([c:38]6[cH:39][c:40]([CH2:44][C:45](=[O:46])[CH3:47])[cH:41][cH:42][cH:43]6)=[O:48])[CH2:35][CH2:36]5)[cH:26][cH:27][cH:28]4)[cH:18][c:19]23)[cH:6][cH:7][cH:8]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]([NH:9][c:10]2[c:11]([C:50](=[O:51])[NH2:52])[cH:12][n:13][c:14]3[c:15]([CH3:49])[cH:16][c:17]([S:20](=[O:21])(=[O:22])[c:23]4[cH:24][c:25]([C:29](=[O:30])[N:31]5[CH2:32][CH2:33][N:34]([C:37]([c:38]6[cH:39][c:40]([CH2:76][C:75]([NH:74][CH2:73][CH:72]([c:64]7[cH:63][cH:62][c:61]([O:60][CH2:53][c:54]8[cH:55][cH:56][cH:57][cH:58][cH:59]8)[c:70]8[c:65]7[cH:66][cH:67][c:68](=[O:71])[nH:69]8)[O:88][Si:89]([CH3:90])([CH3:91])[C:92]([CH3:93])([CH3:94])[CH3:95])([CH3:86])[CH3:87])[cH:41][cH:42][cH:43]6)=[O:48])[CH2:35][CH2:36]5)[cH:26][cH:27][cH:28]4)[cH:18][c:19]23)[cH:6][cH:7][cH:8]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-6937c5b40a744b6fbfd96d166291467e
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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