Methanol → 4-Hydroxy-3,3-dimethyl-2-oxa-8-azaspiro[4.5]decane
Reaction equation
[CH3:24][OH:25].[OH:1][CH:2]1[C:3]([CH3:22])([CH3:23])[O:4][CH2:5][C:6]12[CH2:7][CH2:8][N:9]([C:12]([O:13][CH2:14][c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)=[O:21])[CH2:10][CH2:11]2>>[OH:1][CH:2]1[C:3]([CH3:22])([CH3:23])[O:4][CH2:5][C:6]12[CH2:7][CH2:8][NH:9][CH2:10][CH2:11]2Participants
3
Sources & evidence
- ORD record
- ord-b89079bd92004542bad2b9a8fff083e7
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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