Nitric Acid → HCID 178418731, compound

HRID 9456Notes

Reaction equation

HRID 9456 reaction equation
[CH2:1]([C:8]1[CH:17]=[C:16]2[C:11]([C:12]([OH:18])=[CH:13][CH:14]=[N:15]2)=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:19]([C:26]1[CH:27]=[C:28]2[C:33](=[CH:34][CH:35]=1)[N:32]=[CH:31][CH:30]=[C:29]2[OH:36])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[N+:37]([O-:40])([OH:39])=[O:38]>>[CH2:1]([C:8]1[CH:17]=[C:16]2[C:11]([C:12]([OH:18])=[C:13]([N+:37]([O-:39])=[O:38])[CH:14]=[N:15]2)=[CH:10][CH:9]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1.[CH2:19]([C:26]1[CH:27]=[C:28]2[C:33](=[CH:34][CH:35]=1)[N:32]=[CH:31][C:30]([N+:37]([O-:40])=[O:38])=[C:29]2[OH:36])[C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1

Participants

5

Reactant 3

HCID 944Nitric AcidHCID 178418774HCID 178418774, compoundHCID 178419100HCID 178419100, compound

Product 2

HCID 178418731HCID 178418731, compoundHCID 178418920HCID 178418920, compound

Procedure

The method described in Part D of Example 10 was used to treat 7-benzylquinolin-4-ol or 6-benzylquinolin-4-ol with nitric acid to provide 7-benzyl-3-nitroquinolin-4-ol or 6-benzyl-3-nitroquinolin-4-ol, respectively, as solids.

Sources & evidence

ORD record
ord-784d2dd1f34043149cecc0d483a46e48
Source dataset
uspto-grants-2006_08
Patent number
US07091214B2

Reaction notes

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