4-Fluorobiphenyl → 1-Chloro-3-(4'-fluoro-4-biphenylyl)-butan-3-ol

HRID 945617Notes

Reaction equation

HRID 945617 reaction equation
[Cl:1][CH2:2][CH2:3][CH:4]([CH3:5])[c:6]1[cH:7][cH:8][c:9](-[c:12]2[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]2)[cH:10][cH:11]1.[Cl:32][CH2:33][CH2:34][C:35](=[O:36])[Cl:37].[F:19][c:20]1[cH:21][cH:22][c:23](-[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[cH:30][cH:31]1.[F:38][c:39]1[cH:40][cH:41][c:42](-[c:43]2[cH:44][cH:45][c:46]([C:47](=[O:48])[CH2:49][CH2:50][Cl:51])[cH:52][cH:53]2)[cH:54][cH:55]1>>[Cl:1][CH2:2][CH2:3][C:4]([CH3:5])([c:6]1[cH:7][cH:8][c:9](-[c:12]2[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]2)[cH:10][cH:11]1)[OH:36]

Participants

5

Reactant 4

HCID 94614-FluorobiphenylHCID 693643-Chloropropionyl chlorideHCID 203020144-(4-Chlorobutan-2-yl)-4'-fluoro-1,1'-biphenylHCID 203027244'-Fluoro-4-(3-chloropropionyl)-biphenyl

Product 1

HCID 203028961-Chloro-3-(4'-fluoro-4-biphenylyl)-butan-3-ol

Sources & evidence

ORD record
ord-d0ebb334e2fe4b4a8cb8c9540240e05a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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