(1-methyl-1H-imidazol-4-yl)methanamine → 2-(1-(4-fluorobenzyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-4-methyl-N-((1-methyl-1H-imidazol-4-yl)methyl)thiazole-5-carboxamide

HRID 945856Notes

Reaction equation

HRID 945856 reaction equation
[CH3:24][n:25]1[cH:26][n:27][c:28]([CH2:30][NH2:31])[cH:29]1.[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][n:7]2[n:8][cH:9][n:10](-[c:13]3[s:14][c:15]([C:19](=[O:20])[OH:21])[c:16]([CH3:18])[n:17]3)[c:11]2=[O:12])[cH:22][cH:23]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][n:7]2[n:8][cH:9][n:10](-[c:13]3[s:14][c:15]([C:19](=[O:20])[NH:31][CH2:30][c:28]4[n:27][cH:26][n:25]([CH3:24])[cH:29]4)[c:16]([CH3:18])[n:17]3)[c:11]2=[O:12])[cH:22][cH:23]1

Participants

3

Reactant 2

HCID 2795114(1-methyl-1H-imidazol-4-yl)methanamineHCID 579198022-(1-(4-fluorobenzyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-4-methylthiazole-5-carboxylic acid

Product 1

HCID 594812932-(1-(4-fluorobenzyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-4-methyl-N-((1-methyl-1H-imidazol-4-yl)methyl)thiazole-5-carboxamide

Sources & evidence

ORD record
ord-cd659344e24b4c36b2818f62c37028ae
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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