(2-Methoxyethyl)(methyl)amine → tert-Butyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}-3-{3-[(2-methoxyethyl)methylcarbamoyl]benzyloxy}piperidine-1-carboxylate
Reaction equation
[CH3:45][O:46][CH2:47][CH2:48][NH:49][CH3:50].[Cl:1][C:2](=[O:3])[c:4]1[cH:5][c:6]([CH2:7][O:8][CH:9]2[CH2:10][N:11]([C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:12][CH2:13][CH:14]2[c:15]2[cH:16][cH:17][c:18]([O:21][CH2:22][CH2:23][CH2:24][O:25][CH2:26][c:27]3[c:28]([O:33][CH3:34])[cH:29][cH:30][cH:31][cH:32]3)[cH:19][cH:20]2)[cH:42][cH:43][cH:44]1>>[C:2](=[O:3])([c:4]1[cH:5][c:6]([CH2:7][O:8][CH:9]2[CH2:10][N:11]([C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:12][CH2:13][CH:14]2[c:15]2[cH:16][cH:17][c:18]([O:21][CH2:22][CH2:23][CH2:24][O:25][CH2:26][c:27]3[c:28]([O:33][CH3:34])[cH:29][cH:30][cH:31][cH:32]3)[cH:19][cH:20]2)[cH:42][cH:43][cH:44]1)[N:49]([CH2:48][CH2:47][O:46][CH3:45])[CH3:50]Participants
3
Sources & evidence
- ORD record
- ord-38227fbbbc0f4f96a8cf106176865407
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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