3-(Chloromethyl)-5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole → GSK-971086

HRID 945926Notes

Reaction equation

HRID 945926 reaction equation
[CH3:1][c:2]1[nH:3][c:4]2[cH:5][cH:6][c:7]([C:15]#[N:16])[c:8]([C:11]([F:12])([F:13])[F:14])[c:9]2[cH:10]1.[Cl:17][CH2:18][c:19]1[n:20][o:21][c:22](-[c:24]2[cH:25][c:26]([C:30]([F:31])([F:32])[F:33])[cH:27][cH:28][cH:29]2)[n:23]1>>[CH3:1][c:2]1[n:3]([CH2:18][c:19]2[n:20][o:21][c:22](-[c:24]3[cH:25][c:26]([C:30]([F:31])([F:32])[F:33])[cH:27][cH:28][cH:29]3)[n:23]2)[c:4]2[cH:5][cH:6][c:7]([C:15]#[N:16])[c:8]([C:11]([F:12])([F:13])[F:14])[c:9]2[cH:10]1

Participants

3

Reactant 2

HCID 27366223-(Chloromethyl)-5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazoleHCID 533093462-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Product 1

HCID 86620664GSK-971086

Sources & evidence

ORD record
ord-447a8edb0b9e449b9149107c26329e4b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…