Dichloromethane → 17-Ethyl-1-hydroxy-12-[2'-(4"-acetoxyacetylamino-3"-ethoxycyclohexyl)-1'-methylvinyl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo-[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetraone
Reaction equation
[C:57]([CH3:58])(=[O:59])[O:60][CH2:61][C:62](=[O:63])[Cl:64].[CH2:1]([CH3:2])[CH:3]1[C:4](=[O:56])[CH2:5][CH2:6][CH:7]([CH3:55])[CH:8]([C:42](=[CH:43][CH:44]2[CH2:45][CH:46]([O:51][CH2:52][CH3:53])[CH:47]([NH2:50])[CH2:48][CH2:49]2)[CH3:54])[O:9][C:10](=[O:41])[CH:11]2[CH2:12][CH2:13][CH2:14][CH2:15][N:16]2[C:17](=[O:40])[C:18](=[O:39])[C:19]2([OH:38])[CH:20]([CH3:37])[CH2:21][CH:22]([O:35][CH3:36])[CH:23]([CH:24]([O:32][CH3:33])[CH2:25][CH:26]([CH3:31])[CH2:27][C:28]([CH3:30])=[CH:29]1)[O:34]2.[CH2:65]([Cl:66])[Cl:67]>>[CH2:1]([CH3:2])[CH:3]1[C:4](=[O:56])[CH2:5][CH2:6][CH:7]([CH3:55])[CH:8]([C:42](=[CH:43][CH:44]2[CH2:45][CH:46]([O:51][CH2:52][CH3:53])[CH:47]([NH:50][C:62]([CH2:61][O:60][C:57]([CH3:58])=[O:59])=[O:63])[CH2:48][CH2:49]2)[CH3:54])[O:9][C:10](=[O:41])[CH:11]2[CH2:12][CH2:13][CH2:14][CH2:15][N:16]2[C:17](=[O:40])[C:18](=[O:39])[C:19]2([OH:38])[CH:20]([CH3:37])[CH2:21][CH:22]([O:35][CH3:36])[CH:23]([CH:24]([O:32][CH3:33])[CH2:25][CH:26]([CH3:31])[CH2:27][C:28]([CH3:30])=[CH:29]1)[O:34]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-6a057e5311b64b1085c9898738478bd0
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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