HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 946244Generated: November 3, 2026
Ammonia → 5-amino-2-(2,6-difluorophenyl)-N-[1-methyl-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazol-4-yl]-1,3-thiazole-4-carboxamide
https://huagongshe.com/reaction/946244
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | tert-butyl (+/-)-2-(2,6-difluorophenyl)-4-(1-methyl-5-(3-(trifluoromethyl)piperazin-1-yl)-1H-pyrazol-4-ylcarbamoyl)thiazol-5-ylcarbamate | HCID 86680082 | — |
| Product | 5-amino-2-(2,6-difluorophenyl)-N-[1-methyl-5-[3-(trifluoromethyl)piperazin-1-yl]pyrazol-4-yl]-1,3-thiazole-4-carboxamide | HCID 78103932 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Validation data from https://doi.org/10.1039/C8SC04228D |
|---|
| ORD ID | ord-f6695b75ee2e4210a21045b5b27d0acb |
|---|
| Source note | Validation data from https://doi.org/10.1039/C8SC04228D |
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