Acetate → 3-Amino-5-bromo-1-methyl-1,2-dihydropyridin-2-one

HRID 946248Notes

Reaction equation

HRID 946248 reaction equation
[Br:15][c:16]1[c:17](=[O:24])[n:18]([CH3:23])[cH:19][c:20]([Br:22])[cH:21]1.[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)=[NH:14].[C:25](=[O:26])([O-:27])[O-:28].[Cs+:29].[Cs+:30].[O-:38][C:39]([CH3:40])=[O:41].[O-:42][C:43]([CH3:44])=[O:45].[O:31]1[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1.[Pd+2:37]>>[NH2:14][c:16]1[c:17](=[O:24])[n:18]([CH3:23])[cH:19][c:20]([Br:22])[cH:21]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 136809Benzophenone imineHCID 36143503,5-Dibromo-1-methylpyridin-2(1H)-one

Product 1

HCID 529112683-Amino-5-bromo-1-methyl-1,2-dihydropyridin-2-one

Sources & evidence

ORD record
ord-f33ef163d5fc43668623e35637596523
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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