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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 946337Generated: October 26, 2026

Dichloromethane → 5-Amino-N-[2-({[(2-chloro-6-fluorophenyl)carbonyl]amino}methyl)-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamide

https://huagongshe.com/reaction/946337

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTetrahydrofuranHCID 8028—
ReactantDiisopropylethylamineHCID 81531—
Reactant2-Chloro-6-fluorobenzoyl chlorideHCID 2736547—
Reactant5-amino-N-[2-(aminomethyl)-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamideHCID 59487494—
Product5-Amino-N-[2-({[(2-chloro-6-fluorophenyl)carbonyl]amino}methyl)-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)-1H-pyrazole-4-carboxamideHCID 24809712—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-fba51290feaf49c6827532580eb536ea
Source noteValidation data from https://doi.org/10.1039/C8SC04228D