Potassium Cation → tert-butyl 3-(4-(2-(3-ethylureido)-6-fluorobenzo[d]thiazol-5-yl)-2-oxopyridin-1(2H)-yl)pyrrolidine-1-carboxylate

HRID 946370Notes

Reaction equation

HRID 946370 reaction equation
[Br:1][c:2]1[c:3]([F:17])[cH:4][c:5]2[c:6]([n:7][c:8]([NH:10][C:11](=[O:12])[NH:13][CH2:14][CH3:15])[s:9]2)[cH:16]1.[K+:51].[K+:52].[K+:53].[O:18]=[c:19]1[n:20]([CH:34]2[CH2:35][N:36]([C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[CH2:37][CH2:38]2)[cH:21][cH:22][c:23]([B:25]2[O:26][C:27]([CH3:28])([CH3:29])[C:30]([CH3:31])([CH3:32])[O:33]2)[cH:24]1.[OH2:54].[P:46]([O-:47])([O-:48])([O-:49])=[O:50]>>[c:2]1(-[c:23]2[cH:22][cH:21][n:20]([CH:34]3[CH2:35][N:36]([C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[CH2:37][CH2:38]3)[c:19](=[O:18])[cH:24]2)[c:3]([F:17])[cH:4][c:5]2[c:6]([n:7][c:8]([NH:10][C:11](=[O:12])[NH:13][CH2:14][CH3:15])[s:9]2)[cH:16]1

Participants

6

Reactant 5

HCID 813Potassium Cation3×HCID 962WaterHCID 1061PhosphateHCID 596030721-(5-Bromo-6-fluoro-benzothiazol-2-yl)-3-ethyl-ureaHCID 59603106HCID 59603106, compound

Product 1

HCID 59603078tert-butyl 3-(4-(2-(3-ethylureido)-6-fluorobenzo[d]thiazol-5-yl)-2-oxopyridin-1(2H)-yl)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-d49c86f97dc5421d8f6a1795345da21d
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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